La presión para publicar reduce la calidad de los estudios científicos

NATURE.- The quality problem has reared its head in ways that Price could not have anticipated. Mainstream scientific leaders increasingly accept that large bodies of published research are unreliable. But what seems to have escaped general notice is a destructive feedback between the production of poor-quality science, the responsibility to cite previous work and the compulsion to publish.

The quality problem has been widely recognized in cancer science, in which many cell lines used for research turn out to be contaminated. For example, a breast-cancer cell line used in more than 1,000 published studies actually turned out to have been a melanoma cell line. The average biomedical research paper gets cited between 10 and 20 times in 5 years, and as many as one-third of all cell lines used in research are thought to be contaminated, so the arithmetic is easy enough to do: by one estimate, 10,000 published papers a year cite work based on contaminated cancer cell lines. Metastasis has spread to the cancer literature. | Daniel Sarewitz

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